Intravascular granulocyte kinetics in acute leukemia.

Advances in Hematopoietic Stem Cell Mobilization and Peripheral Blood Stem Cell Transplantation

Hematopoietic stem/progenitor cells (HSPCs) which give rise to different blood cell types are present within the bone marrow microenvironment, especially in flat bones such as skull, vertebrae, pelvis and chest. Interacting factors such as stromal derived factor-1/CXCR4, very late antigen-4/vascular cell adhesion molecule-1, Lymphocyte function-associated antigen-1/ intercellular adhesion molec...

Patterns of granulocyte kinetics in acute myelogenous and myelomonocytic leukemia.

Neutrophil and monocyte kinetics in a case of cyclic neutropenia.

The kinetics of neutrophilic granulocytes half disappearance time shortened to 2.3 hr. and monocytes were examined simulMoreover, the intravascular granulocyte dietaneously in a patient suffering from cyclic tribution changed in favor of the marginal neutropenia. During the remission phase of granulocyte pool. During the neutropenic the disease the observed kinetic data for phase, the intravasc...

Acute Myeloid Leukemia Presenting as Intracerebral Granulocytic Sarcoma.

The CNS involvement of acute myeloid leukemia (AML) is more commonly manifest as meningeal involvement. Rarely it may present as intravascular tumor aggregates called granulocytic sarcoma which presents as intracranial hemorrhage. We are presenting a case of intracranial, intra-parenchymal granulocytic sarcoma (other names: chloroma, extramedullary myeloblastoma), presenting as acute hemiplegia...

Acute promyelocytic leukemia: results of treatment by daunorubicin.

Daunorubicin induces complete remissions during the first 5 days (25#{176}/o) or due to in about 500/0 of patients with acute prosepsis during the second and third week myelocytic leukemia. The median duration (25#{176}/o). Long-term survivals are more freof these remission is 26 mo. Failures are quent than in the other acute granulocytic mainly due to hemorrhages as a result of leukemias. diss...